Alcohol and Drug Abuse Research Center
Center for Depression, Anxiety and Stress Research
McLean Imaging Center
Clinical Unit Based Research
Mailman Research Center
Shervert H. Frazier Research Institute
Clinical Trials
Inventions for License
Research News


Drug Discovery and Drug Screening

Assay for Prediction of Analgesic Efficacy
Invention MCL 2668.0   (US Patent 7,860,552)
Borsook Contact McLean for more information
Methods for Identifying Anatomical and Molecular Targets for Analgesic Therapy
Invention MCL 2669.0
Borsook Contact McLean for more information

Novel Therapeutic Compounds

Salvinorin Compounds and Uses Thereof
Invention MCL 2549.0, 20101.0   (US Patent 7,629,475)
Beguin More details
Compounds for the Treatment of Parkinson's Disease
Invention MCL 2608.0
Kim More details
Mixed Kappa/Mu Opioids and Uses Thereof
Invention MCL 2245.0   (US Patent 7,271,173)
Neumeyer More details
N-Substituted Derivatives of Morphinan and Uses Thereof
Invention MCL 1937.0   (US Patents 6,844,438 and 7,291,628)
Neumeyer More details
Modified Apomorphine Derivatives
Invention MCL 2566.0, 3487.0, 3817.0   (US Patent 7,648,995)
Neumeyer More details

Therapeutic Methods

Dopamine D4 Receptor-Selective Antagonists as Treatment for Attention Deficit-Hyperactivity Disorder
Invention MCL 1778.0   (US Patent 6,747,029)
Baldessarini More details
Treatment of Sequelae of Psychiatric Disorders
Invention MCL 2725.0
Borsook More details
Treatment of Depression
Invention MCL 1793.0   (US Patent 6,528,518)
Carlezon More details
Treatment and Diagnosis of Diseases Characterized by Mitochondrial Dysfunction
Invention MCL 3180.0
Cataldo More details
Methods for Treatment of Mood Disorders
Invention MCL 3088.0
Cohen More details
Methods of Treating Pathological Gambling and other Compulsive Disorders
Invention MCL 3268.0
Elman More details
G-Substrate for Treatment and Prevention of Parkinson's Disease
Invention MCL 3344.0
Isacson More details
Rab3B for the Treatment and Prevention of Parkinson's Disease
Invention MCL 3345.0
Isacson More details
Methods for the Diagnosis and Treatment of Parkinson's Disease
Invention MCL 20165.0
Isacson More details
Drug-Enhanced Neurofeedback Using Functional Magnetic Resonance Imaging
Invention MCL 3823.0
Knight More details
Implantable Electroconvulsive Therapy
Invention MCL 3483.0
Morales More details
Compounds as Treatment for Depression or Dysthymia
Invention MCL 168.0
Renshaw More details
Treatment of Mental Conditions Including Depression
Invention MCL 187.0   (US Patent 6,258,794)
Renshaw More details
Compounds for the Treatment of Attention Deficit Hyperactivity Disorder (ADHD)
Invention MCL 1629.0
Renshaw More details
Agents for Treatment of Cognitive Disorders
Invention MCL 1811.0
Renshaw More details
Improved Methods for the Treatment of Attentional Disorders
Invention MCL 2645.0
Teicher More details

Stem Cell, Cell-Based Therapies

Stem Cell Method for Treating Neurodegenerative Diseases
Invention MCL 3182.0
Cataldo More details
Dopaminergic Neurons Differentiated from Embryonic Cells for Treating Neurodegenerative Disorders
Invention MCL 2127.0
Isacson More details
Cell Sorting Codes for Purification of Neural Stem Cells and Stem Cell-Derived Neurons
Invention MCL 3661.0
Isacson More details
Neural Stem Cells Derived from Induced Pluripotent Stem Cells
Invention MCL 3797.0
Isacson More details
Cell-Specific Enhancer Domains for Neuronal Gene Expression
Invention MCL 180.0, 1827.0   (US Patents 6,525,189, 7,037,715 and 7,585,962)
Kim More details
Generation of iPS Cells by Direct Protein Delivery
Invention MCL 20164.0
Kim More details