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MCL 1628.0: Compounds for Alcohol and Opiate Abuse

Perry Renshaw, M.D., Ph.D.

Background and Description

Phosphorus-31 magnetic resonance spectroscopy experiments indicate that persons who are dependent upon alcohol and opiates have decreased brain levels of phospholipids. The invention comprises the use of a class of compounds known, through studies on healthy individuals, to have activity consistent with increased phospholipid synthesis.

Potential Commercial Uses

The invention comprises a method of treating alcohol or opiate abuse or dependency, using an agent selected from a class of compounds known to cause increased phospholipid synthesis. Few, if any, effective treatments currently exist for treatment of substance abuse or dependence.

Publication and Patent Status

McLean Hospital is the owner of pending U.S. and European patent application claiming this invention.

Licenses Available

Exclusive licenses to this technology are available in certain fields of use.

For more information, please contact:

Anne Ritter, Licensing Manager
Partners Research Ventures and Licensing
(617) 954-9529